Further Insights into direct nose to brain delivery:
An intra-oral spray delivers an active ingredient directly into the bloodstream rather than relying on primary processing by the digestive system. It is widely known in the medical and supplement communities that oral sprays are the fastest, most effective way to take medicines, nutrients, minerals and vitamins.
The first evidence of drug absorption via the buccal mucosa was noted over 100 years ago. Subsequently, in 1879, sublingual administration of nitroglycerin was reported to successfully alleviate the symptoms of classic angina pectoris. Since then, oral mucosal drug delivery has drawn more and more attention because of its potential advantages over other routes of delivery.
– M. Milind Thosar
Compared to secretions of the GI tract, saliva is a relatively mobile fluid with less mucin, limited enzymatic activity and virtually no proteases. In comparison, the buccal and sublingual regions have less enzymes and lower enzyme activity, which is especially favorable to protein and peptide delivery.
What is LymeplexPLUSTM ? What is it’s ingredient LP2 How is it made?
LP2™, the unique differentiating ingredient in all ORB Services LLC products, is comprised non-exclusively of amino acids, proteins and enzymes. The constituent enzymes are produced by microbes colonized in a proprietary technology referred to as the “LP2 Bioreactor”. The manufacturer is increasing the number of their Bioreactors to satisfy product demand.
The Manufacturers’ Bioreactor contains a proprietary media near saturation levels with various species of microbes. Within their Bioreactor, various microbes have varying roles in the LP2TM production process. The process requires accurate temperature, oxygenation and hydration levels. It depends significantly on clean hydration. Carbon and nitrogen level management is also necessary. All of which occur utilizing the complex proprietary process control systems developed by the manufacturer.
Bioreactors are sometimes compared to fermentation tanks for brewing beer or decomposition systems relying on various microbial species to support the various phases of these specific processes. This is true in the sense that microbes will do most of the work. Past that it is like comparing a Navy Seal team to a garbage collection company. Each person is important to get the specific job done but the skill set is considerably different.
The bioreactor initially extracts the primary molecular building blocks for the amine and carboxyl groups which must then combine into peptides which will subsequently combine to form into many and varied proteins.
The Manufacturer’s Bioreactor is designed specifically to restrict overall molecule availability to Carbon (C), Oxygen (O), Nitrogen (N) and Hydrogen (H). Amino acids are formed from an amino group, a group comprised of C, O, N and/or H, and at least one carboxyl group. This inherently restricts production to beneficial, non-toxic amino acids. No toxic substances or toxic chemicals are used in or added to the process, nor are any toxins or toxic substances produced by the process. This is a clear distinction when comparing the Manufacturer’s Bioreactor to other microbe activated systems. The specificity and accuracy with which the amino acid selection is achieved is important to applications that LymeplexPLUSTM targets.
The manufacturer’s Bioreactors employ a natural process by definition as there has been no genetic modification of any microbe or any organism in any part of any of our manufacturer’s process.
The LymeplexPLUS™ product is retrieved from the bioreactor using proprietary extraction and filtration processes without compromise to microbes or the bioreactor environment. Reverse engineering the process using the LymeplexPLUS™ product is impossible. The combination of microbes, and the environment in which they colonize, are proprietary, all natural, and non-toxic. Independent laboratory tests confirm that the LymeplexPLUS™ product is non-toxic and not harmful to organisms. Bacteriological and toxicology testing confirm the product is safe for consumption by plants, animals and humans and is not harmful to organics.